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Biology: explore STEM content (page 2 of 50) · openstem
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Biology
Cells, genetics, ecology and physiology on openstem — flashcards, notes, quizzes, sketches and flowcharts shared by the community. Study free, or clone anything into your library.
A small population loses genetic diversity through drift, suffers inbreeding depression, declines further, and becomes even more vulnerable to further genetic loss and stochastic events. This self-reinforcing decline is called:
AA genetic bottleneckBAn extinction vortexCThe edge effectDAssisted migration
What is the complement system, in broad terms?1 / 10
The complement system is a group of roughly 30 blood plasma proteins, produced mainly by the liver, that circulate in an inactive state and become sequentially activated in a cascade to help destroy pathogens and amplify both innate and adaptive immune responses.
In synthetic biology, what does it mean for an engineered genetic circuit component to be orthogonal to its host?
AIt operates using distinct transcriptional or translational machinery so that it does not cross-react with the host cell's endogenous regulatory networkBIt is physically inserted into the host genome at a 90-degree angle relative to the origin of replicationCIt is derived entirely from genes native to the host organismDIt requires no promoter because it is constitutively active at a fixed rate
Allele and Genotype Frequencies Consider a biallelic autosomal locus with alleles A and a . Define allele frequencies: Derivation Under random mating in an infinite population with no selection, mutation, or migration, gametes unite at r
Sensory Physiology and Transduction Mechanisms Every sense organ solves the same underlying problem: convert some feature of the physical or chemical world into a change in membrane potential that the nervous system can interpret. Despite t
What is a principal advantage of shotgun metagenomic sequencing over 16S rRNA amplicon sequencing for characterizing a microbial community?
AIt is substantially cheaper per sample than 16S amplicon sequencing.BIt captures viruses, archaea, and eukaryotic microbes alongside bacteria and enables strain-level taxonomic resolution plus direct functional gene annotation, rather than being restricted to bacterial/archaeal 16S sequence.CIt works even when only trace amounts of degraded DNA are available.DIt requires no bioinformatic analysis after sequencing.
Why do most cultured somatic cells stop dividing after a finite number of divisions (the Hayflick limit)?
AThey run out of available nutrients in any culture medium regardless of replenishment.BProgressive telomere shortening, due to the end-replication problem and low telomerase activity in most somatic cells, eventually triggers a persistent DNA damage response that enforces permanent cell-cycle arrest.CMitochondrial DNA is completely degraded after a fixed number of divisions.Dp53 is permanently inactivated after several rounds of division.
Biology
Biology · L5 · Aging Biology and Cellular Senescence
What is auxin, and where is it produced in a shoot?1 / 10
Auxin (mainly indole-3-acetic acid, IAA) is a plant hormone synthesized primarily in the shoot apical meristem and young leaves. It is transported downward through the stem in a polar, cell-to-cell fashion via PIN efflux carrier proteins, and it drives cell elongation, apical dominance, and tropic responses.
What is a promoter, and how is its position defined relative to the transcription start site?1 / 10
A promoter is a DNA sequence upstream of a gene that RNA polymerase (directly, in bacteria, or via transcription factors, in eukaryotes) recognises and binds to initiate transcription. Positions are numbered relative to the transcription start site (+1): upstream sequences are negative (e.g. -10, -35), downstream sequences are positive. The promoter itself lies almost entirely upstream of +1.
Enzymes of DNA replication DNA replication depends on a coordinated team of enzymes and proteins, each with a specific job in copying the genome quickly and accurately before a cell divides. Key enzymes and their roles Together, these enzym
Asexual reproduction is a way of producing offspring from a single parent, with no mate needed. Because there is only one parent, the offspring are genetically identical (or nearly identical) copies of that parent — clones.