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Biology: explore STEM content (page 8 of 50) · openstem
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Biology
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A health condition caused, at least in part, by a change (mutation) in an organism's DNA or by an abnormal number of chromosomes. Some genetic disorders are inherited from parents; others arise from a new mutation.
What is deep homology, and why did it force a revision of how comparative biologists think about morphological novelty?1 / 10
Deep homology is the conservation of the same underlying gene regulatory circuitry across lineages whose morphological structures are not themselves homologous by classical criteria — the structures may have arisen independently, but the genetic machinery that builds them was inherited from a common ancestor and redeployed. The Pax6/eyeless case is paradigmatic: insect compound eyes and vertebrate camera eyes were long treated as textbook convergent evolution, yet both are built under the control of orthologous Pax6-class transcription factors. Deep homology reframes 'independent evolution' claims — the toolkit gene is homologous even when the resulting organ's architecture is not, so morphological convergence at the anatomical level can sit atop genetic conservation at the regulatory level.
Biology
Biology · L5 · The Conserved Developmental Toolkit
A neuron is a nerve cell — a special cell built to receive a message, carry it along, and pass it on to the next cell. Neurons are the basic building blocks of the whole nervous system.
Animal Lifespans at a Glance An animal's lifespan is the total length of time it is alive, from birth or hatching all the way to death. Lifespan is not the same thing as how long an animal takes to grow up — a mouse reaches adulthood in jus
In CRISPR-Cas9 gene editing, what is the job of the guide RNA?
ATo provide energy for the Cas9 protein to moveBTo match up with the target DNA sequence and lead Cas9 to the right spotCTo repair the DNA after it has been cutDTo copy the entire genome before editing begins
What did Takahashi and Yamanaka demonstrate in 2006, and what are the four original Yamanaka factors?1 / 10
Takahashi and Yamanaka showed that forced retroviral expression of just four transcription factors, Oct4, Sox2, Klf4, and c-Myc, collectively OSKM, is sufficient to reprogram a terminally differentiated mouse fibroblast into an induced pluripotent stem cell functionally and molecularly resembling an embryonic stem cell.
Biology
Biology · L5 · Reprogramming and Regenerative Biology
Turgor pressure is the outward push of water inside a plant cell against its rigid cell wall. When cells are full of water, this pressure keeps them firm, which is what holds a plant upright.
Photorespiration occurs when rubisco binds which molecule instead of CO2, and what is a consequence of this reaction?
AWater; it produces excess NADPHBOxygen; it produces 2-phosphoglycolate and releases previously fixed carbon as CO2CNitrogen; it fixes additional nitrogen into amino acidsDMalate; it stores carbon for later use
The Nitrogen Cycle in Depth Nitrogen makes up about 78% of Earth's atmosphere, yet most living things cannot use it in that form. Atmospheric nitrogen exists as N2, two nitrogen atoms locked together by an extremely strong triple bond that
Cell Signaling and Cell Cycle Regulation Multicellular life depends on cells communicating accurately with one another and responding appropriately to their internal state. Two systems make this possible: signal transduction pathways that c
What is the glomerular filtration rate (GFR), and what is a typical value in a healthy adult?1 / 10
GFR is the volume of filtrate formed by both kidneys per minute, typically ~125 mL/min (~180 L/day). Only ~1-1.5 L is excreted as urine each day because more than 99% of the filtrate is reabsorbed along the nephron.
A herring gull chick pecks more at an artificial bill with an exaggerated red spot than at a real parent bill. This demonstrates:
AHabituation to a repeated stimulusBA supernormal stimulus exploiting the rules of a sign-stimulus releasing mechanismCOperant conditioning through reinforcementDLatent learning expressed without reward