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Biology: explore STEM content (page 11 of 50) · openstem
Explore STEM Content
Search the community's STEM library — free to study, yours to make your own.
Biology
Cells, genetics, ecology and physiology on openstem — flashcards, notes, quizzes, sketches and flowcharts shared by the community. Study free, or clone anything into your library.
The Circulatory System: Your Body's Delivery Service Every cell in your body needs oxygen and nutrients to survive. The circulatory system delivers them by pumping blood through a network of tubes called blood vessels. At the center of the
What does xylem transport, and in which direction does it move?1 / 10
Xylem transports water and dissolved mineral ions from the roots upward to the stems and leaves. Movement is one-directional, driven mainly by transpiration pulling water up through dead, hollow xylem cells.
Molecular Basis of Neoplastic Transformation Cancer arises through the clonal accumulation of somatic mutations that deregulate the genes controlling cell proliferation, survival, and genomic integrity. Two broad gene classes are implicated
Biology
Biology · L5 · Cancer Biology: From Mutation to Malignancy
Explain the chemistry of a cytosine base editor (CBE) and why it does not require a double-strand break to install a point mutation.1 / 9
A cytosine base editor fuses a catalytically impaired Cas9 nickase (Cas9 D10A, which nicks only the non-target strand) to a cytidine deaminase domain (derived from APOBEC or AID family enzymes) and a uracil glycosylase inhibitor (UGI). The deaminase converts cytosine to uracil within the single-stranded DNA exposed in the R-loop formed when the guide RNA binds its target, at a position set by the editing window (typically protospacer positions 4-8 counting from the PAM-distal end).
Countercurrent heat exchange in a limb primarily functions to:
AIncrease heat loss from the extremity to speed coolingBTransfer heat from warm arterial blood to cool venous blood, retaining it in the coreCEqualize blood pressure between arteries and veinsDGenerate heat directly through friction between opposing blood flows
Biology
Biology · L4 · Thermoregulation and Osmoregulation Quiz
Describe the two-step mechanism by which NMDA receptor activation requires both glutamate binding and postsynaptic depolarization — the basis of coincidence detection.1 / 10
NMDA receptors are simultaneously ligand-gated and voltage-gated. At resting membrane potential, an extracellular Mg2+ ion occludes the channel pore, so glutamate binding alone is insufficient to permit ion flow. Only when the postsynaptic membrane is substantially depolarized — typically by concurrent, strong AMPA receptor activation from repetitive presynaptic firing — is the Mg2+ ion electrostatically expelled from the pore, permitting Ca2+ and Na+ influx.
A hypha (plural: hyphae) is a single thread-like filament that makes up the body of a multicellular fungus. Each hypha is a tube of cytoplasm surrounded by a rigid cell wall made of chitin, and it grows by extending at its tip.
Fur, Feathers, Scales, and Skin Every animal has a covering on the outside of its body. This covering is not just for looks. It has an important job to do, like keeping the animal warm, dry, safe, or hidden. Why Coverings Matter Animals liv
Biophysics and Single-Molecule Methods Single-molecule biophysical methods observe individual biomolecules one at a time rather than averaging over a bulk population, revealing mechanistic detail — discrete conformational states, stepwise m
Biology
Biology · L5 · Biophysics and Single-Molecule Methods