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Biology
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Biology: explore STEM content (page 45 of 50) · openstem
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What stimulates ADH (vasopressin) release, and where is it synthesized and released?1 / 9
ADH is synthesized in the hypothalamus and released from the posterior pituitary. Release is stimulated primarily by rising blood osmolality detected by hypothalamic osmoreceptors, and secondarily by large drops in blood volume or pressure detected by baroreceptors.
Biology
Biology · L4 · Hormonal Regulation Of Fluid Balance
Asexual vs. Sexual Reproduction Across the Tree of Life Across the tree of life, organisms reproduce in two broad ways: asexually, using genetic material from a single parent, or sexually, by combining genetic material from two parents. Nei
Biology
Biology · L3 · Asexual vs. Sexual Reproduction Across the Tree of Life
What chemical feature allows RIG-I to distinguish many viral RNA replication intermediates from host cytoplasmic mRNA?
AThe presence of an uncapped 5' triphosphate or diphosphate group, absent from 5'-capped host mRNA.BThe presence of a poly-A tail, which only viral RNA has.CRIG-I cannot distinguish viral RNA from host RNA under any circumstances.DThe presence of thymine bases instead of uracil.
Bioinformatic Sequence Analysis Comparative sequence analysis — aligning, scoring, and modeling relationships among DNA, RNA, and protein sequences — underlies nearly every downstream biological inference in genomics, from identifying a gen
Why must GnRH be released in a pulsatile pattern to sustain normal FSH/LH secretion?
AContinuous GnRH exposure causes receptor downregulation and desensitization, paradoxically suppressing gonadotropin releaseBContinuous GnRH exposure always increases FSH/LH release furtherCPulsatile release has no functional significanceDGnRH cannot cross into the bloodstream unless released in pulses
A sigmoidal (rather than hyperbolic) velocity-vs-substrate curve is characteristic of an enzyme that shows:
AA single active site with no communication between subunitsBPositive cooperativity among multiple subunits, where binding at one site increases affinity at the othersCPure competitive inhibition onlyDNo regulation of any kind
Biology
Biology · L4 · Enzyme Regulation and Allostery Quiz
What is a genome-wide association study (GWAS), and what statistical model is typically fit at each variant to test for association with a binary disease phenotype?1 / 10
A GWAS tests hundreds of thousands to millions of common genetic variants (typically SNPs) across the genome for statistical association with a trait or disease in a large cohort, without any prior hypothesis about which genes are involved.
According to the size principle, which motor units are recruited first when a muscle produces a small, light-intensity force?
ASmall, low-threshold Type I motor unitsBLarge, high-threshold Type IIx motor unitsCAll motor units are recruited simultaneously regardless of sizeDOnly motor units with the highest innervation ratio
Summarize the overall products of the light-dependent reactions of photosynthesis that feed into the Calvin cycle.1 / 10
The light-dependent reactions, occurring across the thylakoid membrane, use light energy captured by photosystems II and I to split water (releasing O2), pump protons to build a proton-motive force that drives ATP synthase, and pass electrons through an electron transport chain ultimately reducing NADP+ to NADPH. These two products, ATP and NADPH, are the energy and reducing-power currency exported to the stroma to power carbon fixation in the Calvin cycle; the light reactions alone fix no carbon.
Biology
Biology · L4 · Photosynthesis: Light Reactions and Rubisco
Animal Sounds in Nature Animals make many different sounds. If you close your eyes and just listen, you can often guess which animal is nearby by the sound it makes. Matching Sounds to Animals Here are some common animal sounds and the anim
Describe the amyloidogenic processing pathway of amyloid precursor protein (APP) that generates amyloid-beta (Aβ) peptides in Alzheimer's disease.1 / 10
APP is processed via two competing pathways. In the non-amyloidogenic pathway, alpha-secretase cleaves APP within the Aβ domain, precluding Aβ formation. In the amyloidogenic pathway, beta-secretase (BACE1) first cleaves APP at the N-terminus of the Aβ domain, releasing soluble APPβ and leaving a membrane-bound C99 fragment.
What is a keystone species, and why is its removal so consequential?1 / 10
A species that exerts an ecological influence disproportionate to its abundance, such that its removal triggers a cascade of change throughout the community. Sea otters are a classic example: by preying on sea urchins, they keep urchin populations low enough for kelp forests to persist. Remove the otters, and urchins overgraze the kelp, collapsing the habitat that many other species depend on.
Biology
Biology · L4 · Community Interactions and Succession
Describe how parietal cells secrete hydrochloric acid into the stomach lumen, and what enzyme provides the substrate needed for this process.1 / 10
Parietal cells use carbonic anhydrase to combine CO2 and water into carbonic acid, which dissociates into H+ and bicarbonate; the H+ is actively pumped into the stomach lumen against a steep concentration gradient by an H+/K+-ATPase (the proton pump) in the apical membrane, while the bicarbonate is exchanged for chloride at the basolateral membrane (the chloride shift), with chloride then following H+ into the lumen through apical channels to combine and form hydrochloric acid. This mechanism can achieve a luminal pH as low as about 1-2, roughly a million-fold higher H+ concentration than in the blood.
Biology
Biology · L4 · Digestive Enzymes, Motility, and Regulation