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Biology: explore STEM content (page 16 of 50) · openstem
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Biology
Cells, genetics, ecology and physiology on openstem — flashcards, notes, quizzes, sketches and flowcharts shared by the community. Study free, or clone anything into your library.
Food Groups and a Balanced Diet Every day, your body needs a mix of different nutrients to grow, repair itself, and have enough energy to move, think, and stay healthy. No single food provides everything you need, which is why eating a vari
Why does a cytosine base editor avoid the indels and translocations associated with standard Cas9 nuclease editing?
AIt uses a guide RNA with no PAM requirement at all.BIt uses a Cas9 nickase rather than a double-strand-cutting nuclease, so only one DNA strand is nicked while the deaminase-edited base is copied by the cell's own mismatch repair, avoiding a double-strand break intermediate.CIt does not require any Cas protein at all.DIt works only on RNA, never on genomic DNA.
Warm-Blooded and Cold-Blooded Animals Every animal needs to control its body temperature to stay alive. But different animal groups do this in very different ways. Making Your Own Heat Mammals and birds are warm-blooded. Their bodies burn e
Phylogenomics and Comparative Genomics Phylogenomics extends classical phylogenetics to genome-scale data, confronting the reality that different genomic loci can carry genuinely different evolutionary histories, and using patterns of seque
Biology
Biology · L5 · Phylogenomics and Comparative Genomics
An enzyme has a very low Km for its substrate compared to a second enzyme acting on the same substrate. What does this indicate?
AThe low-Km enzyme has a higher affinity for the substrate and reaches half-maximal rate at a lower substrate concentrationBThe low-Km enzyme has a lower affinity for the substrate and requires more substrate to become saturatedCThe low-Km enzyme necessarily has a higher Vmax than the second enzymeDKm provides no information about substrate affinity
Biology
Biology · L4 · Enzyme Kinetics and Metabolism Quiz
Classification means sorting living things into groups based on features they share, such as how they get food, how many cells they have, or what their bodies are made of.
State Anfinsen's thermodynamic hypothesis and describe the experimental evidence (the ribonuclease A refolding experiment) that supported it.1 / 9
Anfinsen's thermodynamic hypothesis holds that a protein's native, functional three-dimensional structure is (for many single-domain proteins) the thermodynamically most stable conformation under physiological conditions, and that this structure is determined entirely by the protein's amino acid sequence — meaning a denatured protein should be able to spontaneously refold to its correct native structure without any additional information, given the right solution conditions.
Biology
Biology · L5 · Protein Folding and Molecular Chaperones
Virology Basics Viruses are obligate intracellular parasites: they carry genetic information but no independent metabolism or ribosomes, and must hijack a host cell's machinery to replicate. Their enormous diversity in genome type and repli