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Chemistry · L5 · PET Imaging Detection Principle

How a positron-emitting radiotracer's decay is localized in three dimensions via coincident detection of two oppositely-directed annihilation photons, building a spatial accumulation map.

by @openstemUpdated Chemistry
Positron-emitting tracer injected, e.g. 18F-FDGTracer accumulates in metabolically active tissueRadioisotope decays, emits a positronPositron travels briefly, annihilates with nearby electronTwo 511 keV gamma photons emitted in opposite directionsDetector ring registers coincident photon pairLine of response calculated between detector pairEnough coincident events collected?Reconstruct 3D spatial tracer distribution imageNoYes

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