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Chemistry · L4 · Protein structure levels, bottom-up

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The four levels of protein structure as a chemical build-up, from covalent peptide bonds to non-covalent R-group interactions.

by @openstemUpdated Chemistry
Primary structureAmino acid sequence(peptide bonds, covalent)Secondary structureAlpha helix / beta sheet(backbone H-bonds)Tertiary structureFolded 3D shape(R-group interactions)Disulfide bonds(S–S, covalent)Hydrophobic packing(nonpolar R groups bury inward)Ionic bonds(charged R groups pair)Quaternary structureMultiple chains assembled(same R-group forces, between chains)

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