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Biology · L5 · Selectin-Mediated Leukocyte Rolling Adhesion

The multivalent, fast on/off lectin-glycan interaction that slows a circulating leukocyte along activated endothelium.

Biology
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Endothelium Activated by Inflammatory SignalSelectins Displayed on Endothelial SurfaceSialyl Lewis X Glycans on Leukocyte Bind SelectinsFast On and Off Binding Slows LeukocyteLeukocyte Rolls Along Vessel WallFirm Adhesion and Transmigration Follow
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