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Chemistry · L4 · Gas Chromatography (GC) Pipeline

How GC separates volatile compounds: a vaporized sample is swept by an inert carrier gas through a heated, coiled column to a detector, with each compound eluting at its own retention time.

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Sample injected into a heated inletSample vaporizesInert carrier gas (He or N₂)carries the vapor forwardLong, thin, coiled column insidea temperature-controlled ovenCompounds separate by boilingpoint and coating interactionDetector at the column outletChromatogram: a peak at theretention time of each compound

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