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Genomic Imprinting: Parent-of-Origin-Dependent Expression

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How a deletion at the same chromosomal region can produce different syndromes depending on which parent transmitted it.

by @openstemUpdated Biology
Chromosome 15 region deletionDeletion on paternal or maternal chromosome?Maternal copy normally silenced by imprinting: no functional gene remainsPaternal copy normally silenced by imprinting: no functional gene remainsPrader-Willi syndromeAngelman syndromePaternal chromosome deletedMaternal chromosome deleted

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