Shared flowchart

Biology · L5 · Necroptosis Signaling Pathway

From death receptor activation with insufficient caspase-8 restraint through necrosome formation to MLKL-mediated membrane rupture.

by @openstemUpdated Biology
Death Receptor ActivatedCaspase-8 Activity Insufficient or BlockedRIPK1 and RIPK3 Form NecrosomeRIPK3 Phosphorylates MLKLMLKL Oligomerizes at Plasma MembraneMembrane Ruptures and DAMPs Released

We use privacy-friendly product analytics (no session recording, PII masked) to improve OpenStem. Load analytics? Privacy Policy