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Chemistry · L3 · Paper Chromatography vs TLC

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Paper chromatography and thin-layer chromatography (TLC) use different stationary phases and speeds, but the same Rf idea.

by @openstemUpdated Chemistry
Same mixture spotted on a baselineChoose a stationary phaseAbsorbent paper stripSilica or alumina layer on a rigid plateSolvent soaks slowly through paper fibresSolvent moves quickly through the thin solid layerSpots migrate over tens of minutes, can streakSpots migrate in minutes, stay sharp and compactSame Rf = distance to spot / distance to solvent frontPaper chromatographyThin-layer chromatography (TLC)

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