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Chemistry · L5 · Supramolecular Chemistry: Host–Guest Recognition & Preorganization · flowchart

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by @openstemUpdated Chemistry
Guest speciesapproaches host cavityCavity size & donor geometrymatch the guest?Preorganized binding sitesengage with minimal reorganizationSteric clash orunmet donor-acceptor sitesStable complexhigh association constantWeak or no bindinglow association constantGood matchPoor match

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